V3I1P61

Formulation and evaluation of microcapsule for peptic ulcer treatment

Madhuri Kowachi^1*, Anju Mishra²

Abstract

Formulation and evaluation of microcapsules for peptic ulcers aim to create sustained-release systems, often using polymers like chitosan, guar gum, or HPMC, to prolong drug action in the stomach, improve patient compliance, and enhance bioavailability, typically involving methods like emulsion cross-linking or ionotropic gelation, and assessed via parameters like % yield, entrapment efficiency, particle size, and in vitro release studies to achieve controlled delivery for drugs like omeprazole, lafutidine.

Keywords:

Microcapsule , chitosan, HPMC, ulcer, gelation , Lafutidine