V2I6P52

‘Dentinogenesis Imperfecta’ – A Review

Dr. B. Lakshmana Rao^1*

Abstract

A genetic dental condition called Dentinogenesis Imperfecta (DI) alters the mineralization, structure, and formation of dentin.  It causes teeth that are discolored, brittle, and vulnerable to wear, fracture, and early loss.  DI is frequently linked to mutations in the dentin sialophosphoprotein (DSPP) gene and can occur with or without systemic involvement.  Three types of DI have been identified: Type I is linked to osteogenesis imperfecta, Type II is non-syndromic and also referred to as hereditary opalescent dentin, and Type III is the uncommon Brandywine isolate that exhibits pulp exposures and shell tooth characteristics.  Patients usually exhibit pulp obliteration, translucency, rapid attrition, amber or blue-gray tooth discoloration, and bulbous crowns with cervical constrictions.  On radiography, Type III teeth have shell-like appearances, short roots, and obliterated pulp chambers.  Clinical and radiographic evidence, family history, and genetic testing are used to confirm the diagnosis.  Amelogenesis imperfecta, dental fluorosis, and dentin dysplasia are examples of differential diagnoses.

Keywords:

Dentinogenesis Imperfecta, Hereditary Opalescent Dentin, Capdepont Teeth, Dysplastic Dentin