V1I9P7

Overcoming Challenges in Oligos Manufacturing: Within an Enterprise Framework

Ritesh Thakur^1*

Abstract

This article explores the diverse and intricate challenges associated with the manufacturing of oligonucleotides, which are synthesized DNA fragments crucial for various applications in research, diagnostics, and therapeutics. The manufacturing process of oligos is highly complex, encompassing numerous technical and logistical hurdles that must be addressed to ensure both efficiency and quality. We will examine the specific challenges in oligonucleotide production, including ensuring high fidelity in synthesis, managing the variability of starting materials, and maintaining stringent quality control standards throughout the production process. Additionally, we will examine how contemporary manufacturing solutions can be effectively integrated with enterprise architecture frameworks, particularly SAP, to create a robust and streamlined operational model. By harnessing advanced technological innovations and integrating them into an established enterprise system, manufacturers can overcome long-standing challenges in the oligonucleotide synthesis industry, leading to improved productivity, reduced costs, and enhanced product reliability. This article will offer insights into these strategies and their potential impact on the industry landscape.

Keywords: Oligos, Manufacturing, MES, Production Planning, Detailed Scheduling, Synthetic DNA, SAP, Capacity Planning, SAP Detailed Scheduling board, Production order